<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0034-7418</journal-id>
<journal-title><![CDATA[Revista Colombiana de Ciencias Químico - Farmacéuticas]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. colomb. cienc. quim. farm.]]></abbrev-journal-title>
<issn>0034-7418</issn>
<publisher>
<publisher-name><![CDATA[Departamento de Farmácia, Facultad de Ciencias, Universidade Nacional da Colombia]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0034-74182018000200289</article-id>
<article-id pub-id-type="doi">10.15446/rcciquifa.v47n2.73972</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Evaluación teórica del desempeño del electrodo, modificado por el oxihidróxido de cobalto (III) en la detección del ácido úrico]]></article-title>
<article-title xml:lang="en"><![CDATA[Theoretical evaluation of the work of the electrode, modified by cobalt (III) oxyhydroxide, in the uric acid detection]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Tkach]]></surname>
<given-names><![CDATA[Volodymyr V.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ivanushko]]></surname>
<given-names><![CDATA[Yana G.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Lukanova]]></surname>
<given-names><![CDATA[Svitlana M.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Kushnir]]></surname>
<given-names><![CDATA[Marta V.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[de Oliveira]]></surname>
<given-names><![CDATA[Sílvio C.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ojani]]></surname>
<given-names><![CDATA[Reza]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Luganska]]></surname>
<given-names><![CDATA[Olga V.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Yagodynets']]></surname>
<given-names><![CDATA[Petró I.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Nacional de Chernivtsi  ]]></institution>
<addr-line><![CDATA[Chernivtsi ]]></addr-line>
<country>Ucrania</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidade Federal de Mato Grosso do Sul  ]]></institution>
<addr-line><![CDATA[Campo Grande MS]]></addr-line>
<country>Brazil</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de Mazandarán  ]]></institution>
<addr-line><![CDATA[Babolsar ]]></addr-line>
<country>República Islámica de Irán</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidad Nacional de Zaporizhzhya Facultad de Biología ]]></institution>
<addr-line><![CDATA[Zaporizhzhya ]]></addr-line>
<country>Ucrania</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>08</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>08</month>
<year>2018</year>
</pub-date>
<volume>47</volume>
<numero>2</numero>
<fpage>289</fpage>
<lpage>300</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0034-74182018000200289&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0034-74182018000200289&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0034-74182018000200289&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN La posibilidad del empleo de oxihidróxido de cobalto como modificador del electrodo en la detección del ácido úrico se investigó desde el punto de vista teórico. Se sugiere el mecanismo del desempeño del compuesto inorgánico en el proceso, y el modelo, correspondiente al proceso, se analizó mediante la teoría de estabilidad lineal y análisis de bifurcaciones. Se concluye que el oxihidróxido de cobalto puede servir como un modificador eficiente, facilitando la oxidación del analito en medio neutro en el modo galvanostático. La inestabilidad monotónica para este caso no puede realizarse, y la oscilatoria es causada por el único factor.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[SUMMARY The possibility of use of cobalt oxyhydroxide as an electrode modifier in the uric acid determination has been investigated from the theoretical point of view. The mechanism of the use of the inorganic compound in the process has been suggested, and the model, correspondent to the process, has been analyzed by means of linear stability theory and bifurcation analysis. It has been concluded that the cobalt oxyhydroxide may serve as an efficient modifier, making easier the analyte oxidation in neutral media in galvanostatic mode. The monotonic instability for this case isn't capable to realize, and the oscillatory behavior is caused by the unique factor.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[ácido úrico]]></kwd>
<kwd lng="es"><![CDATA[sensores electroquímicos]]></kwd>
<kwd lng="es"><![CDATA[electrodos químicamente modificados]]></kwd>
<kwd lng="es"><![CDATA[oxihidróxido de cobalto (III)]]></kwd>
<kwd lng="es"><![CDATA[estado estacionario estable]]></kwd>
<kwd lng="en"><![CDATA[Uric acid]]></kwd>
<kwd lng="en"><![CDATA[electrochemical sensors]]></kwd>
<kwd lng="en"><![CDATA[chemically modified electrodes]]></kwd>
<kwd lng="en"><![CDATA[cobalt (III) oxyhydroxide]]></kwd>
<kwd lng="en"><![CDATA[stable steady-state]]></kwd>
</kwd-group>
</article-meta>
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