<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0034-7434</journal-id>
<journal-title><![CDATA[Revista Colombiana de Obstetricia y Ginecología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Colomb Obstet Ginecol]]></abbrev-journal-title>
<issn>0034-7434</issn>
<publisher>
<publisher-name><![CDATA[Federación Colombiana de Obstetricia y GinecologíaRevista Colombiana de Obstetricia y Ginecología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0034-74342020000300003</article-id>
<article-id pub-id-type="doi">10.18597/rcog.3547</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[SEGURIDAD Y ACEPTABILIDAD DEL SISTEMA INTRAUTERINO LIBERADOR DE LEVONORGESTREL 52 MG EN MUJERES CON HEMORRAGIA UTERINA ANORMAL EN UN CENTRO DE ATENCIÓN AMBULATORIA EN BOGOTÁ, COLOMBIA, 2012-2016]]></article-title>
<article-title xml:lang="en"><![CDATA[Safety and acceptability of the 52 mg levonorgestrel-releasing intrauterine system in women with abnormal uterine bleeding in an ambulatory care center in Bogotá, Colombia, 2012-2016]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sandoval-Vivas]]></surname>
<given-names><![CDATA[Patricia]]></given-names>
</name>
</contrib>
</contrib-group>
<aff id="A">
<institution><![CDATA[,  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2020</year>
</pub-date>
<volume>71</volume>
<numero>3</numero>
<fpage>247</fpage>
<lpage>256</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0034-74342020000300003&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0034-74342020000300003&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0034-74342020000300003&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Objetivo: describir la seguridad y aceptabilidad del uso del sistema intrauterino liberador de levonorgestrel de 52 mg en mujeres con hemorragia uterina anormal.  Materiales y métodos: cohorte retrospectiva en la que se incluyeron mujeres de 18 años o más con diagnóstico de hemorragia uterina anormal, reporte por ultrasonido de tamaño uterino entre 6 y 10 cm de longitud y cavidad endometrial uniforme en toda su longitud, independiente de alteración estructural, a quienes se les colocó para tratamiento el sistema intrauterino liberador de levonorgestrel de 52 mg, en el periodo de 2012 hasta 2016 Se realizó un muestreo por conveniencia. Se midieron variables sociodemográficas y clínicas basales, así como la percepción de la hemorragia por parte de la paciente y la frecuencia de falla, amenorrea, necesidad de histerectomía y eventos adversos, con seguimiento a 12 meses. Se aplicó estadística descriptiva.  Resultados: se evaluaron 200 pacientes, hubo una percepción de mejoría subjetiva del volumen de sangrado y de la frecuencia de incapacidad laboral o asistencia a urgencias. El 90 % de las pacientes registró amenorrea y el 6 % eventos adversos.  Conclusiones: el sistema intrauterino liberador de levonorgestrel de 52 mg es una alternativa segura para el manejo de la hemorragia uterina anormal en mujeres con úteros de tamaño normal y sin al- teraciones submucosas del endometrio. Se requieren estudios aleatorizados en el medio local para evaluar su efectividad y eficiencia respecto a otras alternativas de manejo.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Objective: To describe safety and acceptability with the use of the 52-mg levonorgestrel-releasing intrauterine system in women with abnormal uterine bleeding.  Materials and methods: Retrospective cohort of women 18 years of age and older diagnosed with abnormal uterine bleeding, ultrasound-reported uterine length between 6 and 10 cm and uniform endometrial cavity in its entire length, regardless of structural abnormality, who received treatment with 52-mg levonorgestrel-releasing intrauterine system between 2012 and 2016. Non-probabilistic convenience sampling was carried out. Sociodemographic and clinical baseline variables were measured, as well as patient perception of bleeding and the frequency of failure, amenorrhea, need for hysterectomy and adverse events, over a 12-month follow-up period. Descriptive statistics were applied.  Results: Overall, 200 patients were assessed. A subjective perception of improvement in terms of bleeding volume and frequency of leave of absence or visits to the emergency department was found; 90 % of the patients had amenorrhea, and 6 % experienced adverse events.  Conclusions: The 52-mg levonorgestrel-releasing intrauterine system is a safe option for the management of abnormal uterine bleeding in women with normal uterine size and no submucosal endometrial abnormalities. Local randomized studies are required to assess effectiveness and efficiency in comparison with other management options.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[menorragia]]></kwd>
<kwd lng="es"><![CDATA[dispositivos intrauterinos]]></kwd>
<kwd lng="es"><![CDATA[levonorgestrel]]></kwd>
<kwd lng="es"><![CDATA[hemorragia uterina]]></kwd>
<kwd lng="en"><![CDATA[Menorrhagia]]></kwd>
<kwd lng="en"><![CDATA[intrauterine]]></kwd>
<kwd lng="en"><![CDATA[devices]]></kwd>
<kwd lng="en"><![CDATA[levonorgestrel]]></kwd>
<kwd lng="en"><![CDATA[uterine bleeding]]></kwd>
</kwd-group>
</article-meta>
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