0034-7450 0034-7450 S0034-74502021000300015 10.1016/j.rcp.2020.12.007 Ecuador Ecuador Canada 00 09 2021 00 09 2021 50 3 15 24

1 2020 2 2020 7 1-10 3 World Health Organization 2020 4 World Health Organization 2020 5 2013 59 259-75 6 2020 3 7 2020 8 2020 288 112972 9 1999 13 9210 10 2004 55 1055-7 11 2007 52 233-40 12 2020 288 112954 13 Review ASC 2020 190-7 14 2020 15 2020 16 2012 50 10-22 17 2010 8 8 18 2008 47 566-70 19 2011 139 1163-8 20 2020 35 12-6 21 2020 15