<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0120-1751</journal-id>
<journal-title><![CDATA[Revista Colombiana de Estadística]]></journal-title>
<abbrev-journal-title><![CDATA[Rev.Colomb.Estad.]]></abbrev-journal-title>
<issn>0120-1751</issn>
<publisher>
<publisher-name><![CDATA[Departamento de Estadística - Universidad Nacional de Colombia.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0120-17512012000200007</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Determinants of Birth Intervals in Tamil Nadu in India: Developing Cox Hazard Models with Validations and Predictions]]></article-title>
<article-title xml:lang="es"><![CDATA[Determinantes de los intervalos genésicos en Tamil Nadu (India): desarrollando modelos de riesgos de Cox con validaciones y predicciones]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[SINGH]]></surname>
<given-names><![CDATA[RAJVIR]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[TRIPATHI]]></surname>
<given-names><![CDATA[VRIJESH]]></given-names>
</name>
<xref ref-type="aff" rid="A02"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[KALAIVANI]]></surname>
<given-names><![CDATA[MANI]]></given-names>
</name>
<xref ref-type="aff" rid="A03"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[SINGH]]></surname>
<given-names><![CDATA[KALPANA]]></given-names>
</name>
<xref ref-type="aff" rid="A04"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[DWIVEDI]]></surname>
<given-names><![CDATA[S.N.]]></given-names>
</name>
<xref ref-type="aff" rid="A05"/>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,Hamad Medical Corporation CCS Department Medical Research Centre- Cardiology]]></institution>
<addr-line><![CDATA[Doha ]]></addr-line>
<country>Qatar</country>
</aff>
<aff id="A02">
<institution><![CDATA[,The University of the West Indies Faculty of Science and Agriculture Department of Mathematics & Statistics]]></institution>
<addr-line><![CDATA[Trinidad & Tobago ]]></addr-line>
<country>West Indies</country>
</aff>
<aff id="A03">
<institution><![CDATA[,All India Institute of Medical Sciences Department of Biostatistics ]]></institution>
<addr-line><![CDATA[New Delhi ]]></addr-line>
<country>India</country>
</aff>
<aff id="A04">
<institution><![CDATA[,Max Healthcare Institute Ltd. Clinical Research Department ]]></institution>
<addr-line><![CDATA[New Delhi ]]></addr-line>
<country>India</country>
</aff>
<aff id="A05">
<institution><![CDATA[,All India Institute of Medical Sciences Department of Biostatistics ]]></institution>
<addr-line><![CDATA[New Delhi ]]></addr-line>
<country>India</country>
</aff>
<pub-date pub-type="pub">
<day>20</day>
<month>06</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="epub">
<day>20</day>
<month>06</month>
<year>2012</year>
</pub-date>
<volume>35</volume>
<numero>spe2</numero>
<fpage>289</fpage>
<lpage>307</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0120-17512012000200007&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0120-17512012000200007&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0120-17512012000200007&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[The present study uses data from National Family Health Survey (NFHS-1) 1992-93 (International Institute for Population Sciences 1995) conducted in the state of Tamil Nadu, India. Cox models were developed to analyze the effect of breastfeeding as time varying and time dependent factor on birth intervals. Breastfeeding alone improved the log likelihood up to a higher level in each birth interval. Other factors that entered into the models were: at first birth interval, womens education (high school & above) and working status of women; at second birth interval, survival status of index child alive and husbands education (high school & above), and at third birth interval, breastfeeding more than 22 month were found to be protective factors for next births. Validation of the developed models was done through bootstrapping to predict birth intervals.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Este estudio utiliza datos de la Encuesta Nacional de Salud Familiar (International Institute for Population Sciences 1995) realizada en el estado de Tamil Nadu, India. Se desarrollaron modelos de Cox para analizar el efecto de la lactancia materna cuando varía en el tiempo y el factor tiempo depende de los intervalos genésicos. La lactancia materna sólo mejora la probabilidad de acceder a un nivel más alto en cada intervalo de nacimiento. Otros factores que entraron en los modelos fueron en el intervalo del primer parto: nivel educativo de la madre (secundaria y superior) y trabajo de la madre; en el intervalo del segundo parto: nivel de supervivencia en el índice de vida infantil y nivel educativo del padre (secundaria y superior), y en el intervalo del tercer parto: lactancia materna más 22 meses. Cada uno de los anteriores es un factor protector para ampliar el intervalo entre nacimientos en el estudio. Además, este estudio confirma los modelos desarrollados en los servicios públicos de predicción para los intervalos genésicos.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Cox model]]></kwd>
<kwd lng="en"><![CDATA[Multivariate analysis]]></kwd>
<kwd lng="en"><![CDATA[Validation]]></kwd>
<kwd lng="en"><![CDATA[Predictions]]></kwd>
<kwd lng="es"><![CDATA[análisis multivariado]]></kwd>
<kwd lng="es"><![CDATA[modelo de Cox]]></kwd>
<kwd lng="es"><![CDATA[predicciones]]></kwd>
<kwd lng="es"><![CDATA[validación]]></kwd>
</kwd-group>
</article-meta>
</front><body><![CDATA[  <font size="2" face="verdana">      <p> <b> <font size="4">     <center> Determinants of Birth Intervals in Tamil Nadu in India: Developing Cox Hazard Models with Validations and Predictions </center> </font> </b> </p>      <p> <b> <font size="3">     <center> Determinantes de los intervalos gen&eacute;sicos en Tamil Nadu (India): desarrollando modelos de riesgos de Cox con validaciones y predicciones </center> </font> </b> </p>      <p>     <center> RAJVIR SINGH<sup>1</sup>,  VRIJESH TRIPATHI<sup>2</sup>,  MANI KALAIVANI<sup>3</sup>,  KALPANA SINGH<sup>4</sup>,  S.N. DWIVEDI<sup>5</sup> </center> </p>      <p> <sup>1</sup>Hamad Medical Corporation, CCS Department, Medical Research Centre- Cardiology, Doha, Qatar. Senior consultant. Email: <a href="mailto:rajvir.aiims@gmail.com">rajvir.aiims@gmail.com</a>     <br>  <sup>2</sup>The University of the West Indies, Faculty of Science and Agriculture, Department of Mathematics &amp; Statistics, Trinidad &amp; Tobago, West Indies. Lecturer. Email: <a href="mailto:Vrijesh.Tripathi@sta.uwi.edu">Vrijesh.Tripathi@sta.uwi.edu</a>     <br>  <sup>3</sup>All India Institute of Medical Sciences, Department of Biostatistics, New Delhi, India. Scientist. Email: <a href="mailto:manikalaivani@gmail.com">manikalaivani@gmail.com</a>     ]]></body>
<body><![CDATA[<br>  <sup>4</sup>Max Healthcare Institute Ltd., Clinical Research Department, New Delhi, India. Researcher. Email: <a href="mailto:nkalpanasingh@gmail.com">nkalpanasingh@gmail.com</a>     <br>  <sup>5</sup>All India Institute of Medical Sciences, Department of Biostatistics, New Delhi, India. Professor. Email: <a href="mailto:dwivedi7@hotmail.com">dwivedi7@hotmail.com</a>     <br> </p>  <hr size="1">      <p> <b>     <center> Abstract </center> </b> </p>      <p> The present study uses data from National Family Health Survey (NFHS-1) 1992-93 (International Institute for Population Sciences 1995) conducted in the state of Tamil Nadu, India. Cox models were developed to analyze the effect of breastfeeding as time varying and time dependent factor on birth intervals. Breastfeeding alone improved the log likelihood up to a higher level in each birth interval. Other factors that entered into the models were: at first birth interval, womens education (high school &amp; above) and working status of women; at second birth interval, survival status of index child alive and husbands education (high school &amp; above), and at third birth interval, breastfeeding more than 22 month were found to be protective factors for next births. Validation of the developed models was done through bootstrapping to predict birth intervals. </p>      <p> <b> Key words: </b> Cox model, Multivariate analysis, Validation, Predictions. </p>  <hr size="1">      <p> <b>     <center> Resumen </center> </b> </p>      <p> Este estudio utiliza datos de la Encuesta Nacional de Salud Familiar (International Institute for Population Sciences 1995) realizada en el estado de Tamil Nadu, India. Se desarrollaron modelos de Cox para analizar el efecto de la lactancia materna cuando var&iacute;a en el tiempo y el factor tiempo depende de los intervalos gen&eacute;sicos. La lactancia materna s&oacute;lo mejora la probabilidad de acceder a un nivel m&aacute;s alto en cada intervalo de nacimiento. Otros factores que entraron en los modelos fueron en el intervalo del primer parto: nivel educativo de la madre (secundaria y superior) y trabajo de la madre; en el intervalo del segundo parto: nivel de supervivencia en el &iacute;ndice de vida infantil y nivel educativo del padre (secundaria y superior), y en el intervalo del tercer parto: lactancia materna m&aacute;s 22 meses. Cada uno de los anteriores es un factor protector para ampliar el intervalo entre nacimientos en el estudio. Adem&aacute;s, este estudio confirma los modelos desarrollados en los servicios p&uacute;blicos de predicci&oacute;n para los intervalos gen&eacute;sicos. </p>      ]]></body>
<body><![CDATA[<p> <b> Palabras clave: </b> an&aacute;lisis multivariado, modelo de Cox, predicciones, validaci&oacute;n. </p>  <hr size="1">      <p> Texto completo disponible en <a href="pdf/rce/v35nspe2/v35nspe2a07.pdf">PDF</a> </p>  <hr size="1">      <p> <b> <font size="3"> References </font> </b> </p>       <!-- ref --><p> 1. Anderson, D. L. &amp; Bean, L. L. (1985), 'Birth spacing and fertility limitation: A behavioral analysis of nineteenth century populationl', <i>Demography</i> <b>22</b>, 169-183. &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=000026&pid=S0120-1751201200020000700001&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><!-- ref --><p> 2. Blanchard, R. &amp; Bogaert, A. F. 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Aceptado en marzo de 2012&#93;</b> </center> <hr size="1">      <p> Este art&iacute;culo se puede citar en <i>LaTeX</i> utilizando la siguiente referencia bibliogr&aacute;fica de <i>BibTeX</i>: </p> <code><font size="2">@ARTICLE{RCEv35n2a07,    <br>   AUTHOR = {Singh, Rajvir and Tripathi, Vrijesh and Kalaivani, Mani and Singh, Kalpana and Dwivedi, S.N.},    <br>   TITLE  = {{Determinants of Birth Intervals in Tamil Nadu in India: Developing Cox Hazard Models with Validations and Predictions}},    <br>   JOURNAL = {Revista Colombiana de Estad&iacute;stica},    ]]></body>
<body><![CDATA[<br>  YEAR  = {2012},    <br>  volume = {35},    <br>  number = {2},    <br>  pages  = {289-307}    <br> }</font></code>  <hr size="1"> </font>      ]]></body><back>
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