<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0120-419X</journal-id>
<journal-title><![CDATA[Revista Integración]]></journal-title>
<abbrev-journal-title><![CDATA[Integración - UIS]]></abbrev-journal-title>
<issn>0120-419X</issn>
<publisher>
<publisher-name><![CDATA[Universidad Industrial de Santander]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0120-419X2021000200177</article-id>
<article-id pub-id-type="doi">10.18273/revint.v39n2-2021003</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[The simultaneous application of control interventions can lead to catastrophic epidemic scenarios]]></article-title>
<article-title xml:lang="es"><![CDATA[La aplicación simultánea de intervenciones de control puede llevar a escenarios catastróficos para la población]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[OSUNA]]></surname>
<given-names><![CDATA[OSVALDO]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[VILLAVICENCIO-PULIDO]]></surname>
<given-names><![CDATA[GEISER]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Michoacana de San Nicolás de Hidalgo Instituto de Física y Matemáticas ]]></institution>
<addr-line><![CDATA[Morelia ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Autónoma Metropolitana Unidad Lerma Depto. de Ciencias Ambientales ]]></institution>
<addr-line><![CDATA[México ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<volume>39</volume>
<numero>2</numero>
<fpage>177</fpage>
<lpage>190</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0120-419X2021000200177&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0120-419X2021000200177&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0120-419X2021000200177&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract. We analyze the evolution of an infectious disease if infectious individuals are treated or isolated. The analysis of the model shows catastrophic scenarios for the population in which bringing R  0 below 1 is not enough to decrease the number of infectious individuals. Finally, we show three scenarios for the behavior of the model solutions in which multiple endemic equilibria exist. MSC2010: 34C23, 34C40, 34C55, 34C60, 92D30.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen. Analizamos la evolución de una enfermedad infecciosa si los individuos infecciosos son tratados o aislados. El análisis del modelo muestra escenarios catastróficos para la población en la cual llevarlo por debajo de 1 no es suficiente para disminuir el número de individuos infecciosos. Finalmente, se muestran 3 escenarios posibles para el comportamiento de las soluciones del modelo en los cuales existen equilibrios endémicos múltiples.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Backward bifurcation]]></kwd>
<kwd lng="en"><![CDATA[forward bifurcation]]></kwd>
<kwd lng="en"><![CDATA[Hopf bifurcation]]></kwd>
<kwd lng="en"><![CDATA[treatment]]></kwd>
<kwd lng="en"><![CDATA[isolation]]></kwd>
<kwd lng="es"><![CDATA[Bifurcación hacia atrás]]></kwd>
<kwd lng="es"><![CDATA[bifurcación hacia adelante]]></kwd>
<kwd lng="es"><![CDATA[bifurcación de Hopf]]></kwd>
<kwd lng="es"><![CDATA[tratamiento]]></kwd>
<kwd lng="es"><![CDATA[aislamiento]]></kwd>
</kwd-group>
</article-meta>
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