<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0120-5552</journal-id>
<journal-title><![CDATA[Revista Salud Uninorte]]></journal-title>
<abbrev-journal-title><![CDATA[Salud, Barranquilla]]></abbrev-journal-title>
<issn>0120-5552</issn>
<publisher>
<publisher-name><![CDATA[Fundación Universidad del Norte, División de Ciencias de la]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0120-55522021000100011</article-id>
<article-id pub-id-type="doi">10.14482/sun.37.1.613.2</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Potencial efecto conjunto de los alelos SNP rs3749474T y SNP rs4864548A del gen CLOCK sobre el estado nutricional y cronotipo en jóvenes universitarios]]></article-title>
<article-title xml:lang="en"><![CDATA[Potential Joint Effect of the SNP rs3749474T and SNP rs4864548AAlleles of the CLOCK Gene on Nutritional Status and Chronotype in Young University Students]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pino Astorga]]></surname>
<given-names><![CDATA[Carolina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Roco Videla]]></surname>
<given-names><![CDATA[Ángel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Valladares Vega]]></surname>
<given-names><![CDATA[Macarena]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Bernardo O'Higgins Facultad de Ciencias de la Salud Escuela de Nutrición y Dietética]]></institution>
<addr-line><![CDATA[Santiago ]]></addr-line>
<country>Chile</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Bernardo O'Higgins Facultad de Ciencias de la Salud Programa Magíster en Ciencias químico-biológicas]]></institution>
<addr-line><![CDATA[Santiago ]]></addr-line>
<country>Chile</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Bernardo O'Higgins Centro Integrativo de Biología y Química Aplicada (CIBQA) ]]></institution>
<addr-line><![CDATA[Santiago ]]></addr-line>
<country>Chile</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2021</year>
</pub-date>
<volume>37</volume>
<numero>1</numero>
<fpage>11</fpage>
<lpage>20</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0120-55522021000100011&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0120-55522021000100011&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0120-55522021000100011&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Objetivo: Comparar el estado nutricional, cronotipo y conducta alimentaria que presenta un sujeto que posee simultáneamente los polimorfismos rs3749474T y rs4864548A con respecto a grupos de sujetos que poseen solo uno de dichos polimorfismos. Métodos: La presencia de los polimorfismos se determinó mediante PCR. Se determinó IMC, riesgo cardiovascular y porcentaje de grasa según lo descrito por Durnin y Womersley y la ecuación de Siri. Se aplicó el cuestionario TFEQ-P19 adaptado a población chilena y el cuestionario Horne-Ostberg.  Resultados: El sujeto con ambos polimorfismos presentó obesidad, riesgo cardiovascular y cronotipo trasnochador. Sus puntajes en las dimensiones de alimentación sin control y alimentación emocional fueron bajos. Su puntaje en cuanto a la restricción cognitiva fue el más alto.  Conclusiones: La presencia del haplotipo TA (rs3749474T; rs4864548A) aumentaría la posibilidad de tener un cronotipo de tipo de tipo trasnochador, riesgo de obesidad y riesgo cardiovascular asociado a los centímetros de cintura.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Objective: To compare the nutritional status, chronotype and eating behavior of a subject who simultaneously has the rs3749474T and rs4864548A polymorphisms to groups of subjects who have only one of these polymorphisms.  Methods: The presence of the polymorphisms was established by PCR. BMI, cardiovascular risk, and fat percentage were determined as described by Durnin and Womersley and the Siri equation. The TFEQ-P19 questionnaire (adapted to the Chilean population) and the Hor-ne-Ostberg questionnaire were applied.  Results: The subject with both polymorphisms presented obesity, cardiovascular risk, and late-night chronotype. Its scores on the dimensions of uncontrolled feeding and emotional feeding were low, and its score for cognitive restriction was the highest.  Conclusions: The presence of the TA haplotype (rs3749474; rs4864548A) would increase the possibility of having a late-night type chronotype, risk of obesity, and cardiovascular risk associated with waist centimeters.]]></p></abstract>
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<kwd lng="es"><![CDATA[gen CLOCK]]></kwd>
<kwd lng="es"><![CDATA[obesidad]]></kwd>
<kwd lng="es"><![CDATA[cronotipo]]></kwd>
<kwd lng="en"><![CDATA[CLOCK gene]]></kwd>
<kwd lng="en"><![CDATA[obesity]]></kwd>
<kwd lng="en"><![CDATA[chronotype]]></kwd>
</kwd-group>
</article-meta>
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