<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0120-5633</journal-id>
<journal-title><![CDATA[Revista Colombiana de Cardiología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Colomb. Cardiol.]]></abbrev-journal-title>
<issn>0120-5633</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Colombiana de Cardiologia. Oficina de Publicaciones]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0120-56332017000500458</article-id>
<article-id pub-id-type="doi">10.1016/j.rccar.2017.01.005</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Características clínicas, angiográficas y desenlaces clínicos en adultos mayores de 65 años con síndrome coronario agudo sin elevación del segmento ST]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical and angiographic characteristics, and outcomes in patients over 65 years-old with non-ST elevation acute coronary syndrome]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz]]></surname>
<given-names><![CDATA[James]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gándara]]></surname>
<given-names><![CDATA[Jairo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[M. Sénior]]></surname>
<given-names><![CDATA[Juan]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
<xref ref-type="aff" rid="A a"/>
<xref ref-type="aff" rid="A3"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Antioquia  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Antioquia  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Universitario San Vicente Fundación  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>10</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>10</month>
<year>2017</year>
</pub-date>
<volume>24</volume>
<numero>5</numero>
<fpage>458</fpage>
<lpage>467</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0120-56332017000500458&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0120-56332017000500458&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0120-56332017000500458&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Introducción:  La enfermedad coronaria continúa siendo una causa importante de morbilidad y mortalidad en la población general; existe poca información sobre las características demográficas, clínicas y desenlaces en los pacientes mayores de edad con síndrome coronario agudo en el medio.  Metodología:  Estudio observacional analítico de tipo cohorte prospectivo de pacientes mayores de 18 años de edad con diagnóstico de síndrome coronario agudo sin elevación del segmento ST (SCANST). Se describen las características de los mayores de 65 años y se analiza la asociación entre la edad y los desenlaces clínicos en una cohorte de pacientes con síndrome coronario agudo sin elevación del segmento ST.  Resultados:  Se incluyeron un total de 507 individuos, 277 (55%) con edad &#8805; 65 años. Los pacientes de más edad presentaron mayor prevalencia de diabetes mellitus, hipertensión arterial sistémica y enfermedad coronaria multivaso. El riesgo del desenlace clínico primario compuesto tiempo hasta la muerte, reinfarto no fatal o ataque cerebrovascular fue mayor entre los mayores de 65 años (hazard ratio 1,80; IC 95% 1,09 a 2,97), pero la diferencia dejó de ser significativa en el análisis ajustado (hazard ratio 1,39; IC 95% 0,80 a 2,44).  Discusión:  Los pacientes de edad mayor con síndrome coronario agudo sin elevación del ST tienen características similares a las reportadas en publicaciones de otras latitudes. Sin embargo, a diferencia de lo reportado en la literatura internacional no se logró demostrar que la edad mayor a 65 años constituya un factor de riesgo independiente para desenlaces clínicos adversos en esta población.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Introduction:  Although coronary disease continues to be a major cause of morbidity and mortality in the general population, little is known about the demographic and clinical characteristics, or the outcomes in elderly patients with acute coronary syndrome in the community.  Materials and method:  An observational, prospective, analytical cohort study was conducted on patients over 18 years of age with Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS). The characteristics of those over 65 years are described, as well as the relationships between age and clinical outcomes of a patient cohort with NSTE-ACS.  Results:  Out of a total of 507 patients, there were 277 (55%) aged &#8805; 65 years. These had a higher prevalence of diabetes mellitus, systemic arterial hypertension, and multiple vessel coronary disease. The clinical outcome endpoints that consisted of, time until death, non-fatal re-infarction, or cerebrovascular accident, were higher among those over 65 years-old (Hazard Ratio 1.80; 95% CI; 1.09 - 2.97), but the difference stopped being significant in the adjusted analysis (Hazard Ratio 1.39; 95% CI; 0.80 - 2.44).  Discussion:  The patients over 65 years-old with NSTE-ACS have characteristics similar to those reported in the literature in other countries. However, unlike that reported in the international literature, this study failed to show that being over 65 years is not an independent risk factor for adverse clinical outcomes in this population.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Anciano]]></kwd>
<kwd lng="es"><![CDATA[Angina]]></kwd>
<kwd lng="es"><![CDATA[Infarto de miocardio]]></kwd>
<kwd lng="en"><![CDATA[Elderly]]></kwd>
<kwd lng="en"><![CDATA[Angina]]></kwd>
<kwd lng="en"><![CDATA[Myocardial infarction]]></kwd>
</kwd-group>
</article-meta>
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