<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0120-8705</journal-id>
<journal-title><![CDATA[CES Medicina]]></journal-title>
<abbrev-journal-title><![CDATA[CES Med.]]></abbrev-journal-title>
<issn>0120-8705</issn>
<publisher>
<publisher-name><![CDATA[Universidad CES]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0120-87052023000100095</article-id>
<article-id pub-id-type="doi">10.21615/cesmedicina.7197</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Consideraciones para el manejo del dolor con opioides en pacientes en situación de enfermedad terminal]]></article-title>
<article-title xml:lang="en"><![CDATA[Considerations for the management of pain with opioids in terminally ill patients]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Garzón-Duque]]></surname>
<given-names><![CDATA[Maria Osley]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Orrego-Villegas]]></surname>
<given-names><![CDATA[Elizabeth]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Arenas-Quintero]]></surname>
<given-names><![CDATA[Federico]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fernández-Correa]]></surname>
<given-names><![CDATA[Tomás]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Probst-Girón]]></surname>
<given-names><![CDATA[Natalie Patricia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad CES  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,aff2  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad CES  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2023</year>
</pub-date>
<volume>37</volume>
<numero>1</numero>
<fpage>95</fpage>
<lpage>113</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0120-87052023000100095&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0120-87052023000100095&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0120-87052023000100095&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Introducción:  a medida que aumenta la expectativa de vida y la incidencia de enfermedades crónicas y terminales en América Latina, también crece el número de pacientes que requieren cuidados paliativos, y el personal especializado para su manejo aun es limitado, siendo los médicos generales y cuidadores quienes deben apoyar el manejo del dolor.  Objetivos:  brindar herramientas teóricas y prácticas, tanto a médicos generales como a los parientes de pacientes que requieran cuidados paliativos, que les faciliten realizar un adecuado manejo del dolor en este tipo de pacientes.  Materiales y métodos:  se realizó una revisión narrativa a partir de la sistematización de una búsqueda de diferentes bases de datos, publicaciones de sociedades de cuidados paliativos y anestesia, además de literatura gris.  Resultados:  entre los principales resultados se vio que la mayoría de los pacientes con enfermedades terminales presentan dolor moderado o severo entre sus síntomas principales. De estos un porcentaje importante no presentaba un control adecuado del dolor al momento de fallecer, principalmente por un uso inadecuado de los opioides, entre otros por miedo y desconocimiento por parte de los médicos tratantes y los cuidadores. Los opioides como grupo farmacológico presentan múltiples ventajas para el uso en cuidados paliativos, entre ellos la posibilidad de titularlos a necesidad, realizar rotación de opioides y disponer de múltiples vías de administración.  Discusión:  a pesar de la amplia disponibilidad de opioides continúa habiendo barreras significativas para un adecuado manejo del dolor al final de la vida, entre ellos la falta de conocimiento por parte de los médicos generales.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Introduction:  as life expectancy and the incidence of chronic and terminal diseases increase in Latin America, the number of patients requiring palliative care also grows, while the specialized personnel for its management is still limited, thus general practitioners and caregivers being the ones who must support pain management.  Objectives:  provide theoretical and practical tools, both to general practitioners and to the relatives of patients who require palliative care, that facilitate proper pain management in this type of patient.  Materials and methods:  a narrative review of the literature was carried out through different databases, publications of palliative care and anesthesia societies, as well as grey literature.  Results:  among the main results, it was found that the majority of terminally ill patients present moderate or severe pain among their chief symptoms. Of these, a significant percentage did not present adequate pain control at the time of death, mainly due to inappropriate use of opioids, among others due to fear and ignorance on the part of the treating physicians and caregivers. Opioids as a pharmacological group have multiple advantages for use in palliative care, including the possibility of titrating them as needed, rotating opioids, and having multiple routes of administration.  Discussion: despite the wide availability of opioids, there are still significant barriers to adequate pain management at the end of life, including the lack of knowledge on the part of general practitioners.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[dolor]]></kwd>
<kwd lng="es"><![CDATA[opioide]]></kwd>
<kwd lng="es"><![CDATA[cuidados paliativos]]></kwd>
<kwd lng="en"><![CDATA[pain]]></kwd>
<kwd lng="en"><![CDATA[opioid, palliative care]]></kwd>
</kwd-group>
</article-meta>
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