<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0120-8748</journal-id>
<journal-title><![CDATA[Acta Neurológica Colombiana]]></journal-title>
<abbrev-journal-title><![CDATA[Acta Neurol Colomb.]]></abbrev-journal-title>
<issn>0120-8748</issn>
<publisher>
<publisher-name><![CDATA[Asociación Colombiana de Neurología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0120-87482017000500014</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Genética de las distonías]]></article-title>
<article-title xml:lang="en"><![CDATA[Genetic classification of dystonia]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Arango]]></surname>
<given-names><![CDATA[Gabriel J.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Nacional de Colombia  ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2017</year>
</pub-date>
<volume>33</volume>
<fpage>14</fpage>
<lpage>19</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0120-87482017000500014&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0120-87482017000500014&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0120-87482017000500014&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Con el avance de la secuenciación genética y otras técnicas se ha logrado avanzar de manera significativa en la detección de formas monogénicas de la distonía así como en la contribución de varios factores genéticos en la génesis de esta condición.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[SUMMARY With the refinement of genetic sequencing and many other techniques, monogenic forms of dystonia as well as various genetic contributions and epigenetic factors are now available to guide the clinician in the pursue of an accurate diagnosis of this condition.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[distonía]]></kwd>
<kwd lng="es"><![CDATA[genética]]></kwd>
<kwd lng="es"><![CDATA[mutación (DeCS)]]></kwd>
<kwd lng="en"><![CDATA[Dystonia]]></kwd>
<kwd lng="en"><![CDATA[Genetics]]></kwd>
<kwd lng="en"><![CDATA[Mutation (MeSH)]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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