<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0120-971X</journal-id>
<journal-title><![CDATA[CES Odontología]]></journal-title>
<abbrev-journal-title><![CDATA[CES odontol.]]></abbrev-journal-title>
<issn>0120-971X</issn>
<publisher>
<publisher-name><![CDATA[Universidad CES - Facultad de Odontología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0120-971X2020000200012</article-id>
<article-id pub-id-type="doi">10.21615/cesodon.33.2.2</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Evaluación de la actividad antimicrobiana de los dentífricos basados en propóleos en patógenos orales]]></article-title>
<article-title xml:lang="en"><![CDATA[Evaluation of the antimicrobial activity of propolis toothpastes on oral pathogens]]></article-title>
<article-title xml:lang="pt"><![CDATA[Avaliação da atividade antimicrobial de dentífricos com base em própolis em patógenos orais]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cerveira-Valois-de-Sá]]></surname>
<given-names><![CDATA[Tatiana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Monteiro-Neto]]></surname>
<given-names><![CDATA[Valério]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Carmo]]></surname>
<given-names><![CDATA[Cadidja Dayane Sousa do]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ribeiro]]></surname>
<given-names><![CDATA[Cecília Cláudia Costa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alves]]></surname>
<given-names><![CDATA[Cláudia Maria Coêlho]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Federal de Maranhão  ]]></institution>
<addr-line><![CDATA[São Luís Maranhão]]></addr-line>
<country>Brazil</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Federal de Maranhão  ]]></institution>
<addr-line><![CDATA[São Luís Maranhão]]></addr-line>
<country>Brazil</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Federal de Maranhão  ]]></institution>
<addr-line><![CDATA[São Luís Maranhão]]></addr-line>
<country>Brazil</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<volume>33</volume>
<numero>2</numero>
<fpage>12</fpage>
<lpage>22</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0120-971X2020000200012&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0120-971X2020000200012&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0120-971X2020000200012&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Introducción y objetivo:  La incorporación de propóleos en los dentífricos tiene como objetivo ayudar de manera más efectiva al control y la prevención de patologías orales a través de la eliminación de los patógenos presentes en la biopelícula. Sin embargo, se sabe poco sobre la eficacia antimicrobiana de diferentes productos en el mercado de microorganismos para estas patologías. El objetivo de este estudio fue investigar la acción antimicrobiana de tres dentífricos que contienen propóleos sobre los patógenos orales.  Material y métodos:  Se utilizó el método de difusión en agar para analizar tres dentífricos basados en propóleos, que incluyen: Noplak Max®, Protta® y Forever Bright®. Se utilizó un dentífrico sin propóleos (Malvatrikids®) como control negativo. Los controles positivos fueron 0,2% de clorhexidina diluida adicionalmente al 30% para igualar la concentración de clorhexidina de uno de los dentífricos evaluados, y el extracto de propóleos (Apis Flora®) al 11%. Para la determinación de la actividad antimicrobiana se utilizaron las cepas de Fusobacterium nucleatum y Aggregatibacter actinomycetemcomitans, Enterococcus faecalis, Streptococcus mutans, Lactobacillus acidophilus y Candida albicans.  Resultados:  De los dentífricos probados, Protta® y Forever Bright® mostraron acción inhibitoria contra S. mutans, E. faecalis y microorganismos de C. albicans. El dentífrico Nopla k® mostró baja actividad antimicrobiana, limitándose a S. mutans y E. faecalis. Cuando hubo un efecto antimicrobiano, los diámetros de los halos de inhibición del crecimiento variaron de 9mm a 28,83mm.  Conclusión:  El uso de un dentífrico que contiene propóleos para su uso eventual como complemento terapéutico en odontología está justificado, considerando las actividades farmacológicas.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Introduction and objective:  The incorporation of propolis in dentifrices aims to more effectively assist the control and prevention of oral pathologies through the elimination of pathogens present in the biofilm. However, little is known about the antimicrobial efficacy of different products on the market for microorganisms for these conditions. The aim of this study was to investigate the antimicrobial action of three propolis-containing dentifrices on oral pathogens.  Material and methods:  The agar diffusion method was used to analyze three propolis-based dentifrices, including: Noplak Max®, Protta® and Forever Bright®. A non-propolis dentifrice (Malvatrikids®) was employed as a negative control. Positive controls were 0.2% chlorhexidine, further diluted 30% to match the chlorhexidine concentration of one of the evaluated dentifrices and 11% propolis extract (Apis Flora®). For the determination of antimicrobial activity the strains of Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans, Enterococcus faecalis, Streptococcus mutans, Lactobacillus acidophilus and Candida albicans were used.  Results:  Of the tested dentifrices, Protta® and Forever Bright® showed inhibitory action against S. mutans, E. faecalis and C. albicans microorganisms. Noplak® dentifrice showed low antimicrobial activity, being limited to S. mutans and E. faecalis. When there was an antimicrobial effect, the diameter of the growth inhibition halos ranged from 9mm to 28.83mm.  Conclusion:  The use of a propolis-containing dentifrice for eventual use as a therapeutic adjunct in dentistry is fully justified, considering the pharmacological activities.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo  Introdução e objetivo:  A incorporação de própolis em dentifrícios visa ajudar a controlar e prevenir patologias bucais de maneira mais eficaz, através da eliminação de patógenos presentes no biofilme. No entanto, pouco se sabe sobre a eficácia antimicrobiana de diferentes produtos no mercado de microrganismos para essas patologias. O objetivo deste estudo foi investigar a ação antimicrobiana de três dentifrícios contendo própolis em patógenos orais.  Material e métodos:  O método de difusão em ágar foi utilizado para analisar três dentífricos à base de própolis, incluindo: Noplak Max®, Protta® e Forever Bright®. Um creme dental não própolis (Malvatrikids®) foi usado como controle negativo. Os controles positivos foram 0,2% de clorexidina diluída para 30% para corresponder à concentração de clorexidina de um dos dentifrícios avaliados e 11% de extrato de própolis (Apis Flora®). Para a determinação da atividade antimicrobiana, foram utilizadas as linhagens Fusobacterium nucleatum e Aggregatibacter actinomycetemcomitans, Enterococcus faecalis, Streptococcus mutans, Lactobacillus acidophilus e Candida albicans.  Resultados:  Dos dentifrícios testados, Protta® e Forever Bright® apresentaram ação inibitória contra S. mutans, E. faecalis e microorganismos de C. albicans. O creme dental Noplak® apresentou baixa atividade antimicrobiana, limitada a S. mutans e E. faecalis. Quando houve efeito antimicrobiano, os diâmetros dos halos de inibição de crescimento variaram de 9 a 28,83 mm.  Conclusão:  O uso de um dentifrício contendo própolis para eventual uso como complemento terapêutico em odontologia é totalmente justificado, considerando as atividades farmacológicas.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[enfermedades periodontales]]></kwd>
<kwd lng="en"><![CDATA[caries dental]]></kwd>
<kwd lng="en"><![CDATA[dentífrico]]></kwd>
<kwd lng="en"><![CDATA[propóleos]]></kwd>
<kwd lng="en"><![CDATA[periodontal diseases]]></kwd>
<kwd lng="en"><![CDATA[dental caries]]></kwd>
<kwd lng="en"><![CDATA[dentifrice]]></kwd>
<kwd lng="en"><![CDATA[propolis]]></kwd>
<kwd lng="pt"><![CDATA[doenças periodontais]]></kwd>
<kwd lng="pt"><![CDATA[cárie dentária]]></kwd>
<kwd lng="pt"><![CDATA[creme dental]]></kwd>
<kwd lng="pt"><![CDATA[própolis]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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