<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0120-9957</journal-id>
<journal-title><![CDATA[Revista colombiana de Gastroenterología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Col Gastroenterol]]></abbrev-journal-title>
<issn>0120-9957</issn>
<publisher>
<publisher-name><![CDATA[Asociación Colombiana de Gastroenterología  ]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0120-99572019000300269</article-id>
<article-id pub-id-type="doi">10.22516/25007440.309</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Rol de los antiespasmódicos en el manejo del síndrome de intestino irritable (SII)]]></article-title>
<article-title xml:lang="en"><![CDATA[The role of antispasmodics in managing irritable bowel syndrome]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Costa Barney]]></surname>
<given-names><![CDATA[Valeria Atenea]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ovalle Hernández]]></surname>
<given-names><![CDATA[Alan Felipe]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Universitario San Ignacio  ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2019</year>
</pub-date>
<volume>34</volume>
<numero>3</numero>
<fpage>269</fpage>
<lpage>276</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0120-99572019000300269&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0120-99572019000300269&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0120-99572019000300269&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen El uso de los antiespasmódicos forma parte de la piedra angular del tratamiento en el síndrome de intestino irritable (SII), independientemente del subtipo. Consideramos relevante hacer una revisión de los medicamentos antiespasmódicos disponibles actualmente en Colombia, los cuales son usados crónicamente, de manera frecuente, en esta enfermedad.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Although antispasmodics are the cornerstone of treating irritable bowel syndrome, there are a number of antispasmodic medications currently available in Colombia. Since they are frequently used to treat this disease, we consider an evaluation of them to be important.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Antiespasmódicos]]></kwd>
<kwd lng="es"><![CDATA[síndrome de intestino irritable]]></kwd>
<kwd lng="es"><![CDATA[bromuro de pinaverio]]></kwd>
<kwd lng="es"><![CDATA[bromuro de otilonio]]></kwd>
<kwd lng="es"><![CDATA[mebeverina]]></kwd>
<kwd lng="es"><![CDATA[trimebutina]]></kwd>
<kwd lng="en"><![CDATA[Antispasmodic]]></kwd>
<kwd lng="en"><![CDATA[irritable bowel syndrome]]></kwd>
<kwd lng="en"><![CDATA[pinaverium bromide]]></kwd>
<kwd lng="en"><![CDATA[otilonium bromide]]></kwd>
<kwd lng="en"><![CDATA[Mebeverin]]></kwd>
<kwd lng="en"><![CDATA[trimebutine]]></kwd>
</kwd-group>
</article-meta>
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<surname><![CDATA[Koo]]></surname>
<given-names><![CDATA[JS]]></given-names>
</name>
<name>
<surname><![CDATA[Koo]]></surname>
<given-names><![CDATA[YS]]></given-names>
</name>
<name>
<surname><![CDATA[Kim]]></surname>
<given-names><![CDATA[KO]]></given-names>
</name>
<name>
<surname><![CDATA[Kim]]></surname>
<given-names><![CDATA[YS]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Efficacy of fenoverine and trimebutine in the management of irritable bowel syndrome: multicenter randomized double-blind non-inferiority clinical study]]></article-title>
<source><![CDATA[Korean J Gastroenterol]]></source>
<year>2013</year>
<volume>62</volume>
<numero>5</numero>
<issue>5</issue>
<page-range>278-87</page-range></nlm-citation>
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<ref id="B45">
<label>45</label><nlm-citation citation-type="book">
<source><![CDATA[Trimebutine Maleate and Pinaverium Bromide for Irritable Bowel Syndrome: A Review of the Clinical Effectiveness, Safety and Guidelines]]></source>
<year>2015</year>
<publisher-loc><![CDATA[Ottawa (ON) ]]></publisher-loc>
<publisher-name><![CDATA[Canadian Agency for Drugs and Technologies in Health]]></publisher-name>
</nlm-citation>
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</back>
</article>
