<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0121-0793</journal-id>
<journal-title><![CDATA[Iatreia]]></journal-title>
<abbrev-journal-title><![CDATA[Iatreia]]></abbrev-journal-title>
<issn>0121-0793</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Antioquia]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0121-07932017000100086</article-id>
<article-id pub-id-type="doi">10.17533/udea.iatreia.v30n1a09</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Paciente con síndrome oro-facio-digital tipo II. Reporte del caso]]></article-title>
<article-title xml:lang="en"><![CDATA[Oro-facial-digital syndrome type II. Report of the case]]></article-title>
<article-title xml:lang="pt"><![CDATA[Paciente com síndrome oral-facial-digital tipo II. Reporte do caso]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Edel]]></surname>
<given-names><![CDATA[Tamy]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Zárate-Sanabria]]></surname>
<given-names><![CDATA[Andrés Gabriel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Briceño-Balcázar]]></surname>
<given-names><![CDATA[Ignacio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martínez-Lozano]]></surname>
<given-names><![CDATA[Julio César]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de La Sabana Facultad de Medicina ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de La Sabana Facultad de Medicina ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de La Sabana Facultad de Medicina ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidad de La Sabana Facultad de Medicina ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2017</year>
</pub-date>
<volume>30</volume>
<numero>1</numero>
<fpage>86</fpage>
<lpage>91</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0121-07932017000100086&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0121-07932017000100086&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0121-07932017000100086&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN El síndrome oro-facio-digital (OFD) es un trastorno raro del desarrollo embrionario, cuya incidencia en la población general fluctúa entre menos de 1/1 000 000 y 1/250 000 nacidos vivos. Los pacientes suelen presentar complicaciones del desarrollo de la boca, la cara, las manos y los pies. Hasta el momento se desconoce la mayoría de los genes implicados por lo que el diagnóstico es clínico. Se presenta el caso de un paciente en edad escolar con alteraciones orales, faciales, digitales y auditivas compatibles con el síndrome OFD; por sus características fenotípicas se hizo el diagnóstico de la variante tipo II. La discusión se basa en los criterios para las variantes del síndrome.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[SUMMARY Oro-facial-digital syndrome (OFD) is a rare congenital disorder. Its incidence in the general population ranges from less than 1/1.000.000 to 1/250.000 living births. Patients usually present developmental disorders that affect the mouth, face, hands and feet. So far, most of the genes involved are unknown, so diagnosis is clinical. We report the case of a child with oral, facial, and digital alterations, and hearing impairment suggestive of the OFD syndrome. Phenotype was consistent with the type II variant. Discussion is based on the criteria for variants of the syndrome.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO A síndrome oral-facial-digital (OFD) é um transtorno raro do desenvolvimento embrionário, cuja incidência na população geral flutua entre menos de 1/1 000 000 e 1/250 000 nascidos vivos. Os pacientes normalmente apresentam complicações do desenvolvimento da boca, a face, as manas e os pies. Até o momento se desconhece a maioria dos genes implicados pelo que o diagnóstico é clínico. Se apresenta o caso de um paciente em idade escolar com alterações orais, faciais, digitais e auditivas compatíveis com a síndrome OFD; por suas características fenotípicas se fez o diagnóstico da variante tipa II. A discussão se baseia nos critérios para as variantes da síndrome.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Fisura Labio/Palatina]]></kwd>
<kwd lng="es"><![CDATA[Hipoacusia]]></kwd>
<kwd lng="es"><![CDATA[Síndrome Oro-Facio-Digital]]></kwd>
<kwd lng="es"><![CDATA[Variante OFD tipo II]]></kwd>
<kwd lng="en"><![CDATA[Cleft lip/palate]]></kwd>
<kwd lng="en"><![CDATA[Hearing Loss]]></kwd>
<kwd lng="en"><![CDATA[OFD type II variant]]></kwd>
<kwd lng="en"><![CDATA[Syndrome Oro-Facial-Digital]]></kwd>
<kwd lng="pt"><![CDATA[Fissura Lábio/Palatina]]></kwd>
<kwd lng="pt"><![CDATA[Hipoacusia]]></kwd>
<kwd lng="pt"><![CDATA[Síndrome OralFacial-Digital]]></kwd>
<kwd lng="pt"><![CDATA[Variante OFD tipo II]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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