<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0121-3709</journal-id>
<journal-title><![CDATA[ORINOQUIA]]></journal-title>
<abbrev-journal-title><![CDATA[Orinoquia]]></abbrev-journal-title>
<issn>0121-3709</issn>
<publisher>
<publisher-name><![CDATA[Instituto de Investigaciones de la Orinoquia Colombiana]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0121-37092021000100047</article-id>
<article-id pub-id-type="doi">10.22579/20112629.655</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Uso de los factores de crecimiento presentes en el plasma rico en plaquetas como un tratamiento alternativo de lesiones músculo esqueléticas en animales]]></article-title>
<article-title xml:lang="en"><![CDATA[Use of growth factors present in platelet-rich plasma as an alternative treatment for musculoskeletal lesions in animals]]></article-title>
<article-title xml:lang="pt"><![CDATA[Uso de fatores de crescimento presentes no plasma rico em plaquetas como tratamento alternativo para lesões musculo esqueléticas em animais]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cuadros-Corredor]]></surname>
<given-names><![CDATA[Yesid L]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Siabato-Moreno]]></surname>
<given-names><![CDATA[Juan C]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Roque-Rodriguez]]></surname>
<given-names><![CDATA[Anita]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Pedagógica y Tecnológica de Colombia  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Pedagógica y Tecnológica de Colombia  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de los Llanos Facultad de Ciencias Agropecuarias y Recursos Naturales Escuela de Ciencias Animales]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2021</year>
</pub-date>
<volume>25</volume>
<numero>1</numero>
<fpage>47</fpage>
<lpage>64</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0121-37092021000100047&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0121-37092021000100047&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0121-37092021000100047&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen Se realizó una revisión sistemática del uso de plasma rico en plaquetas (PRP) en animales, seleccionando 105 artículos de referencia, publicados en los últimos 8 años (2012 a 2020) de las revistas Veterinary Medicine International, Scientific Reports, BMC Veterinary Research, Platelets, Biomedicine and Pharmacotherapy entre otras y validadas en las siguientes bases de datos: Pubmed, Web of Science, Sciencedirect, Scielo, Medline, Embase y Scopus. Limitando solo las revistas con altos rankings ayudados con las clasificaciones de revistas por scimago journal. Solo 35 artículos cumplieron los criterios de selección; articulándolo con necesidades actuales en la medicina veterinaria, buscando una nueva biotecnología y proyectándose hacia la medicina regenerativa, basándose en reconstrucción de tejidos vivos para contrarrestar daño o remplazo de función de órganos lesionados. Una de estas herramientas es el plasma rico en plaquetas (PRP) con sus factores de crecimiento (FC) Transformante ß (TGF ß), fibroblástico básico (FGFb), derivado de plaquetas (PDGF), del endotelio vascular (VEGF), tejido conectivo (CTGF) y epidérmico (EGF). Actualmente el (PRP) es un bioestimulante tomado como base por estudios en medicina humana y medicina veterinaria, observando su efectividad en el proceso de consolidación ósea en pacientes clínicos. Se recogieron evidencias científicas presentadas en literatura médica con respecto al PRP como una alternativa de tratamiento en el manejo de fracturas y lesiones músculo esqueléticas, con ello se logra determinar la importancia de la estandarización del procedimiento (PRP) en uso, preparación, almacenamiento y administración.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract A systematic review of platelet-rich plasma (PRP) use in animals was carried out by taking 105 reference articles published during the last 8 years (2012 to 2020) in Veterinary Medicine International, Scientific Reports, BMC Veterinary Research, Platelets, Biomedicine and Pharmacotherapy; they were validated in the following databases: PubMed, Web of Science, ScienceDirect, SciELO, Medline, Embase and Scopus. The search was limited to just journals having a high impact factor; the SCImago journal rank (SJR) indicator (i.e. a sophisticated citation analysis algorithm) was also used. Only 35 of these articles met the selection criteria: i.e. coordinating content with current needs in veterinary medicine, seeking new biotechnological approaches and promoting regenerative medicine based on reconstructing living tissue to counteract damage or replace injured organs&#8217; function. One such tool is platelet-rich plasma (PRP) with its derivative growth factors (GF): transforming growth factor-ß (TGF-ß), basic fibroblast growth factor (bFGF), platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), connective tissue growth factor (CTGF) and epidermal growth factor (EGF). PRP is currently used as a biostimulant, acting as the basis for human and veterinary medicine studies; its effectiveness regarding bone/fracture healing/regeneration in clinical patients has been observed. Scientific evidence in the pertinent medical literature regarding PRP as an alternative treatment for managing fractures and musculoskeletal injuries was collected, thereby determining the importance of standardising the PRP procedure regarding its use, preparation, storage and administration.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo Foi realizada uma revisão sistemática da utilização de plasma rico em plaquetas (PRP) em animais, com 105 artigos de referência, publicados nos últimos 8 anos (2012 a 2020) das revistas Veterinary Medicine International, Scientific Reports, BMC Veterinary Research, Platelets, Biomedicina e Farmacoterapia entre outros e validados nas seguintes bases de dados: Pubmed, Web of Science, Sciencedirect, Scielo, Medline, Embase e Scopus. Limitar apenas os periódicos com classificações altas ajudou com as classificações de periódicos pelo jornal scimago. Dos quais apenas 35 artigos atenderam aos critérios de seleção; articulando-se com as necessidades atuais da medicina veterinária, buscando uma nova biotecnologia e projetando-se na medicina regenerativa, baseada na reconstrução de tecidos vivos para neutralizar danos ou substituição de função de órgãos lesados. Uma dessas ferramentas é o plasma rico em plaquetas (PRP) com seus fatores de crescimento (FC) ß transformador (TGF ß), fibroblasto básico (FGFb), derivado de plaquetas (PDGF), endotelial vascular (VEGF), tecido conjuntivo (CTGF) e epidérmico (EGF). Atualmente (PRP) é um bioestimulante tomado como base para estudos em medicina humana e veterinária, observando sua eficácia no processo de consolidação óssea em pacientes clínicos. Foram coletadas evidências científicas apresentadas na literatura médica a respeito do PRP como alternativa de tratamento no manejo de fraturas e lesões musculoesqueléticas, determinando a importância da padronização do procedimento (PRP) no uso, preparo, armazenamento e administração.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[biotecnología]]></kwd>
<kwd lng="es"><![CDATA[bioestimulante]]></kwd>
<kwd lng="es"><![CDATA[consolidación osea]]></kwd>
<kwd lng="es"><![CDATA[factores de crecimiento]]></kwd>
<kwd lng="es"><![CDATA[fracturas]]></kwd>
<kwd lng="es"><![CDATA[osteoinductor]]></kwd>
<kwd lng="es"><![CDATA[Plaquetas]]></kwd>
<kwd lng="es"><![CDATA[Plasma.]]></kwd>
<kwd lng="en"><![CDATA[biotechnology]]></kwd>
<kwd lng="en"><![CDATA[biostimulant]]></kwd>
<kwd lng="en"><![CDATA[bone consolidation]]></kwd>
<kwd lng="en"><![CDATA[osteoinductive fractures]]></kwd>
<kwd lng="en"><![CDATA[platelet and plasma.]]></kwd>
<kwd lng="pt"><![CDATA[biotecnologia]]></kwd>
<kwd lng="pt"><![CDATA[bioestimulante]]></kwd>
<kwd lng="pt"><![CDATA[consolidação óssea]]></kwd>
<kwd lng="pt"><![CDATA[fatores de crescimento]]></kwd>
<kwd lng="pt"><![CDATA[fraturas]]></kwd>
<kwd lng="pt"><![CDATA[osteoindutor]]></kwd>
<kwd lng="pt"><![CDATA[Plaquetas]]></kwd>
<kwd lng="pt"><![CDATA[Plasma.]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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</person-group>
<article-title xml:lang=""><![CDATA[The application of PRP combined with TCP in repairing avascular necrosis of the femoral head after femoral neck fracture in rabbit]]></article-title>
<source><![CDATA[European review for medical and pharmacological sciences]]></source>
<year>2018</year>
<volume>22</volume>
<numero>4</numero>
<issue>4</issue>
<page-range>903-9</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
