<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0123-7799</journal-id>
<journal-title><![CDATA[TecnoLógicas]]></journal-title>
<abbrev-journal-title><![CDATA[TecnoL.]]></abbrev-journal-title>
<issn>0123-7799</issn>
<publisher>
<publisher-name><![CDATA[Instituto Tecnológico Metropolitano - ITM]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0123-77992021000100257</article-id>
<article-id pub-id-type="doi">10.22430/22565337.1675</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Caracterización morfológica del SARS-CoV-2 mediante microscopía electrónica]]></article-title>
<article-title xml:lang="en"><![CDATA[Morphological characterization of SARS-CoV-2 through electronic microscopy]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Buitrago-Sierra]]></surname>
<given-names><![CDATA[Robison]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Guzmán]]></surname>
<given-names><![CDATA[Álvaro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Santa-Marín]]></surname>
<given-names><![CDATA[Juan Felipe]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Tecnológico Metropolitano  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Instituto Tecnológico Metropolitano  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Instituto Tecnológico Metropolitano  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2021</year>
</pub-date>
<volume>24</volume>
<numero>50</numero>
<fpage>257</fpage>
<lpage>265</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0123-77992021000100257&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0123-77992021000100257&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0123-77992021000100257&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen En este trabajo se realizó una revisión sobre la caracterización morfológica del virus SARS-CoV-2 mediante microscopía electrónica. Se presenta una revisión sobre los aspectos técnicos más relevantes para la preparación de las muestras usadas por varios autores en la literatura. En los detalles finos de la preparación radica el éxito en la obtención de las imágenes. Además, se presentan los detalles relacionados con la bioseguridad. Finalmente, se realiza una descripción de las principales características morfológicas del virus a partir de las imágenes disponibles en la literatura. La morfología del virus se caracteriza por la forma tipo corona en su superficie. La corona está formada por espigas y otras proteínas que forman una capa en la superficie, la cuales se utilizan para unir y penetrar sus células huésped a través de la membrana celular.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract This paper reviews the available literature on the morphological characterization of the SARS-CoV-2 virus by electron microscopy. It presents the most relevant technical aspects for the preparation of samples used by various authors in the field because the details related to said preparation are decisive to obtain the images. In addition, it addresses biosecurity-related factors. Finally, the main morphological characteristics of the virus are described based on the images found in the literature. The morphology of the virus is characterized by a crown-like shape on its surface. Such crowns are composed of spikes and other proteins, forming layers on the surface that are used to penetrate and bind to host cells through the cell membrane.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="es"><![CDATA[microscopía electrónica]]></kwd>
<kwd lng="es"><![CDATA[caracterización morfológica]]></kwd>
<kwd lng="es"><![CDATA[COVID-19]]></kwd>
<kwd lng="en"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="en"><![CDATA[electron microscopy]]></kwd>
<kwd lng="en"><![CDATA[morphology characterization]]></kwd>
<kwd lng="en"><![CDATA[COVID-19]]></kwd>
</kwd-group>
</article-meta>
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