0123-9392 0123-9392 S0123-93922017000200073 10.22354/in.v21i2.661 Colombia 00 06 2017 00 06 2017 21 2 73 73 2012 16 4 4 230-46 2012 11 1S 1S 3 2017 139 2 2 e20163860 2013 56 9 9 1223-31