<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0123-9392</journal-id>
<journal-title><![CDATA[Infectio]]></journal-title>
<abbrev-journal-title><![CDATA[Infect.]]></abbrev-journal-title>
<issn>0123-9392</issn>
<publisher>
<publisher-name><![CDATA[Asociación Colombiana de Infectología.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0123-93922024000300152</article-id>
<article-id pub-id-type="doi">10.22354/24223794.1185</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Análisis de sobrevida en Pediatría por COVID-19 en Colombia]]></article-title>
<article-title xml:lang="en"><![CDATA[Survival analysis in Pediatrics by COVID-19 in Colombia.]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pinilla Gacharná]]></surname>
<given-names><![CDATA[Diana Liceth]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rojas Hernández]]></surname>
<given-names><![CDATA[Juan Pablo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Lambraño Barrera]]></surname>
<given-names><![CDATA[Rafael]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pacheco]]></surname>
<given-names><![CDATA[Robinson]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mesa Monsalve]]></surname>
<given-names><![CDATA[Juan Gonzalo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez Tobar]]></surname>
<given-names><![CDATA[Iván Felipe]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz Díaz]]></surname>
<given-names><![CDATA[Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hoyos Orrego]]></surname>
<given-names><![CDATA[Álvaro Darío]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Garcés Samudio]]></surname>
<given-names><![CDATA[Carlos Guillermo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vinasco Sánchez]]></surname>
<given-names><![CDATA[Luis Gabriel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[López Cubillos]]></surname>
<given-names><![CDATA[Juan Francisco]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Araque Muñoz]]></surname>
<given-names><![CDATA[Paula Andrea]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mejía Rivera]]></surname>
<given-names><![CDATA[Luis Fernando]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Calle Giraldo]]></surname>
<given-names><![CDATA[Juan Pablo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[López Medina]]></surname>
<given-names><![CDATA[Eduardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sarmiento Wilches]]></surname>
<given-names><![CDATA[Patrick Eliana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sosa Ávila]]></surname>
<given-names><![CDATA[Luis Miguel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Jaramillo Jaramillo]]></surname>
<given-names><![CDATA[Catalina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chaucanez Bastidas]]></surname>
<given-names><![CDATA[Yamile]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mendoza Rosado]]></surname>
<given-names><![CDATA[Laura]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Londoño Ruiz]]></surname>
<given-names><![CDATA[Juan Pablo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Beltrán Arroyave]]></surname>
<given-names><![CDATA[Claudia Patricia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ortiz Marín]]></surname>
<given-names><![CDATA[Diana Cristina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández Moreno]]></surname>
<given-names><![CDATA[Derly Carolina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Libre  ]]></institution>
<addr-line><![CDATA[Cali ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Fundación Clínica Infantil Club Noel  ]]></institution>
<addr-line><![CDATA[Cali ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Fundación Valle del Lili  ]]></institution>
<addr-line><![CDATA[Cali ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidad Libre  ]]></institution>
<addr-line><![CDATA[Cali ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Clínica Las Américas Auna  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af6">
<institution><![CDATA[,Clínica Infantil Santa María del Lago  ]]></institution>
<addr-line><![CDATA[Cundinamarca ]]></addr-line>
<country>Bogotá</country>
</aff>
<aff id="Af7">
<institution><![CDATA[,Hospital Pablo Tobón Uribe  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af8">
<institution><![CDATA[,Hospital Universitario San Vicente Fundación  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af9">
<institution><![CDATA[,Clínica Cardio VID  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="A10">
<institution><![CDATA[,Clínica Los Rosales  ]]></institution>
<addr-line><![CDATA[Pereira ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="A11">
<institution><![CDATA[,Fundación Hospital Pediátrico La Misericordia  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A12">
<institution><![CDATA[,Clínica La Colina  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A13">
<institution><![CDATA[,Fundación Clínica Infantil Club Noel, Valle del Cauca  ]]></institution>
<addr-line><![CDATA[Cali ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="A14">
<institution><![CDATA[,Clínica Occidente  ]]></institution>
<addr-line><![CDATA[Cali ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="A15">
<institution><![CDATA[,Centro Médico Imbanaco  ]]></institution>
<addr-line><![CDATA[Cali ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="A16">
<institution><![CDATA[,Clínica Materno infantil San Luis  ]]></institution>
<addr-line><![CDATA[Bucaramanga ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="A17">
<institution><![CDATA[,Clínica Materno infantil San Luis  ]]></institution>
<addr-line><![CDATA[Bucaramanga ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="A18">
<institution><![CDATA[,Hospital Manuel Uribe Ángel  ]]></institution>
<addr-line><![CDATA[Envigado ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="A19">
<institution><![CDATA[,Hospital Infantil Los Ángeles  ]]></institution>
<addr-line><![CDATA[Pasto ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="A20">
<institution><![CDATA[,Clínica Los Rosales  ]]></institution>
<addr-line><![CDATA[Pereira ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="A21">
<institution><![CDATA[,Universidad del Bosque  ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="A22">
<institution><![CDATA[,Pediatra especialista en enfermedades infecciosas  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A23">
<institution><![CDATA[,Pediatra especialista en enfermedades infecciosas  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A24">
<institution><![CDATA[,Pediatra especialista en enfermedades infecciosas  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2024</year>
</pub-date>
<volume>28</volume>
<numero>3</numero>
<fpage>152</fpage>
<lpage>159</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0123-93922024000300152&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0123-93922024000300152&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0123-93922024000300152&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Introducción: La mortalidad asociada al SARS-CoV-2 en la población pediátrica aún es poco conocida. Esto se debe a que los niños suelen presentar síntomas leves o incluso pueden ser asintomáticos, lo que dificulta la identificación y el seguimiento de los casos graves que puedan llevar a la muerte. Así mismo, la infección por SARS-CoV-2 en la población pediátrica se comporta de manera diferente a como lo hace en los adultos. Esta falta de conocimiento es particularmente preocupante en países de ingresos medios y bajos como Colombia, en donde los sistemas de salud pueden no tener la infraestructura necesaria para recopilar y analizar datos de manera efectiva.  Objetivo: Describir la supervivencia por infección por SARS CoV-2/ COVID-19 en población pediátrica diagnosticada en instituciones de salud de atención pediátrica colombianas.  Materiales y métodos: Estudio observacional descriptivo longitudinal con datos retrospectivos en pacientes menores de 17 años que consultaron en 23 instituciones de salud de Colombia entre enero de 2020 y diciembre 2020. Tamaño de la muestra: 23 pacientes.  Resultados: Se registraron 23 casos de pacientes fallecidos por COVID-19 en la población pediátrica en Colombia. La mortalidad fue del 1,9%. El 60,9% de los pacientes fueron menores de 5 años. %, el 56,5% de sexo femenino, el 60,8% de los pacientes presentaban una condición clínica de base asociada y de estos el 17,4% presentaba malnutrición. El uso de antibióticos en casos de coinfección bacteriana se asoció con mayor supervivencia, mientras que el Síndrome de Dificultad Respiratoria (SDR) aguda y las convulsiones se relacionaron con una menor supervivencia con respecto al desenlace final.  Conclusión: La mortalidad por COVID-19 en esta población fue del 1,9%, con una mayor prevalencia en pacientes de sexo femenino menores de 5 años con condición clínica de base asociada, principalmente estado de malnutrición. El síntoma cardinal de presentación fue la dificultad respiratoria y el 100% de los pacientes requirió soporte de oxígeno. El uso de antibióticos en casos de coinfección bacteriana se relacionó con mayor sobrevida, mientras que el síndrome de dificultad respiratoria aguda y las convulsiones contribuyeron a menor tiempo de supervivencia. La variable edad también fue significativa, encontrando mayor riesgo de llegar al desenlace final en menor tiempo en los pacientes menores de 5 años.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Introduction: The mortality associated with SARS-CoV-2 in the pediatric population is still poorly known. This is because children often present with mild symptoms or may even be asymptomatic, making it difficult to identify and monitor severe cases that can lead to death. Likewise, SARS-CoV-2 infection in the pediatric population behaves differently than it does in adults. This lack of knowledge is particularly concerning in low- and middle- income countries like Colombia, where health systems may not have the necessary infrastructure to effectively collect and analyze data.  Objective: To describe survival due to SARS CoV-2/COVID-19 infection in the pediatric population diagnosed in Colombian pediatric care health institutions.  Materials and methods: Longitudinal descriptive observational study with retrospective data in patients under 17 years of age who consulted in 23 health institutions in Colombia between January 2020 and December 2020. Sample size: 23 patients.  Results: 23 cases of patients dying from COVID-19 were recorded in the pediatric population in Colombia. Mortality was 1.9%. 60.9% of the patients were under 5 years of age. %, 56.5% were female, 60.8% of the patients had an associated underlying clinical condition and of these, 17.4% had malnutrition. The use of antibiotics in cases of bacterial coinfection was associated with greater survival, while acute Respiratory Distress Syndrome (RDS) and seizures were related to lower survival with respect to the final outcome.  Conclusion: Mortality from COVID-19 in this population was 1.9%, with a higher prevalence in female patients under 5 years of age with associated underlying clinical condition, mainly malnutrition. The cardinal presenting symptom was respiratory difficulty and 100% of patients required oxygen support. The use of antibiotics in cases of bacterial coinfection was related to longer survival, while acute respiratory distress syndrome and seizures contributed to shorter survival time. The age variable was also significant, finding a greater risk of reaching the final outcome in less time in patients under 5 years of age.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Covid 19]]></kwd>
<kwd lng="es"><![CDATA[niños]]></kwd>
<kwd lng="es"><![CDATA[supervivencia]]></kwd>
<kwd lng="es"><![CDATA[factores asociados]]></kwd>
<kwd lng="es"><![CDATA[mortalidad]]></kwd>
<kwd lng="en"><![CDATA[Covid 19]]></kwd>
<kwd lng="en"><![CDATA[children]]></kwd>
<kwd lng="en"><![CDATA[survival]]></kwd>
<kwd lng="en"><![CDATA[associated factors]]></kwd>
<kwd lng="en"><![CDATA[mortality]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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