<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0124-7107</journal-id>
<journal-title><![CDATA[Universidad y Salud]]></journal-title>
<abbrev-journal-title><![CDATA[Univ. Salud]]></abbrev-journal-title>
<issn>0124-7107</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Nariño]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0124-71072018000100089</article-id>
<article-id pub-id-type="doi">10.22267/rus.182001.113</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Agrandamiento gingival farmacoinducido: Serie de casos]]></article-title>
<article-title xml:lang="en"><![CDATA[Drug-induced gingival enlargement: Series of cases]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Manzur-Villalobos]]></surname>
<given-names><![CDATA[Isabella]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz-Rengifo]]></surname>
<given-names><![CDATA[Iván Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Manzur-Villalobos]]></surname>
<given-names><![CDATA[Daniela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz-Caballero]]></surname>
<given-names><![CDATA[Antonio José]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Cartagena  ]]></institution>
<addr-line><![CDATA[Cartagena ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Colegio Mayor Nuestra Señora del Rosario  ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>15</day>
<month>01</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>15</day>
<month>01</month>
<year>2018</year>
</pub-date>
<volume>20</volume>
<numero>1</numero>
<fpage>89</fpage>
<lpage>96</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0124-71072018000100089&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0124-71072018000100089&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0124-71072018000100089&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Introducción: El agrandamiento gingival (AG) es una condición benigna de la cavidad oral que se caracteriza por el crecimiento excesivo en masa y volumen de la gingiva. Esta lesión no es únicamente provocada por factores hereditarios ni de deficiente higiene oral, sino también por ingesta de medicamentos, entre los cuales se encuentran fármacos antihipertensivos, anticonvulsivantes e inmunosupresores.  Objetivo:  Sensibilizar respecto a la prevención o atención temprana en pacientes con patologías que ameritan el uso de antihipertensivos y anticonvulsivantes, conjuntamente con el odontólogo para tratar o evitar el agrandamiento gingival fármaco inducido (AGFI).  Materiales y métodos:  Se reporta una serie de casos clínicos de pacientes con agrandamiento gingival por distintos fármacos, entre los que se encuentran fenitoina, amlodipino y nifedipino; se aplicaron medidas de fase higiénica periodontal y gingivectomía para obtener mejores efectos.  Resultados: Se obtuvieron resultados satisfactorios con una disminución considerable del AGFI.  Conclusiones:  Es importante el manejo integral en conjunto con el médico tratante para realizar seguimiento del fármaco que pueda encontrarse generando agrandamiento gingival. Emplear un abordaje inicial con estrategias de higiene periodontal, y en casos severos y como último recurso la intervención quirúrgica periodontal con gingivectomía y gingivoplastia.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Introduction:  Gingival enlargement (GA) is a benign condition of the oral cavity that is characterized by the excessive growth of the gingiva in mass and volume. This lesion is not only caused by hereditary factors or poor oral hygiene, but also by the intake of medications, including antihypertensive, anticonvulsant and immunosuppressive drugs.  Objective:  To sensitize the prevention or early care in patients with pathologies that merit the use of antihypertensive and anticonvulsants in conjunction with the dentist, to treat or avoid the drug-induced gingival enlargement (DIGE).  Materials and methods:  A series of clinical cases of patients with gingival enlargement by various drugs are reported, including Phenytoin, Amlodipine and Nifedipine. Periodontal and gingivectomy hygienic phase measures were applied to obtain better effects.  Results:  Satisfactory results were obtained with a considerable decrease in DIGE.  Conclusions:  The integral management is important in conjunction with the treating physician to follow up the drug that can be generating gingival enlargement. It is necessary to employ an initial approach with strategies of periodontal hygiene, and in severe cases and, as last resort, the periodontal surgery with gingivectomy and gingivoplasty.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Sobrecrecimiento gingival]]></kwd>
<kwd lng="es"><![CDATA[antihipertensivos]]></kwd>
<kwd lng="es"><![CDATA[inmunosupresores]]></kwd>
<kwd lng="es"><![CDATA[anticonvulsivantes]]></kwd>
<kwd lng="es"><![CDATA[gingivectomía]]></kwd>
<kwd lng="en"><![CDATA[Gingival overgrowth]]></kwd>
<kwd lng="en"><![CDATA[antihypertensive agents]]></kwd>
<kwd lng="en"><![CDATA[inmunosupressive agents]]></kwd>
<kwd lng="en"><![CDATA[anticonvulsants, gingivectomy]]></kwd>
</kwd-group>
</article-meta>
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