1657-5997 1657-5997 S1657-59972022000402246 10.5294/aqui.2022.22.4.6 Brazil Brazil Brazil Brazil Brazil Brazil 00 12 2022 00 12 2022 22 4

1 2017 26 4 4 2 2017 17 4 4 360-2 3 World Health Organization 2020 4 2018 26 26 5 2019 40 spe spe 6 2013 19 5 5 363 7 2018 66 4 4 693-8 8 2021 30 30 9 2022 30 30 10 2019 9 9 9 11 2019 40 spe spe 12 2020 73 6 6 13 2020 32 5 5 313-8 14 2000 320 7237 7237 726-7 15 2017 64 2 2 242-62 16 2017 39 1 1 68-76 17 2017 2 4 4 18 2016 19 2020 16 2 2 20 2019 28 2 2 286-93 21 2020 29 spe spe 22 2021 17 3 3 195-9 23 2020 2 2 51-60 24 2013 25 2021 18 10 10 5080 26 2020 51 6 6 38-45 27 2017 9 9 2333-64 28 2016 6 9 9 29 2017 19 6 6 30 2021 55 55