<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1657-9534</journal-id>
<journal-title><![CDATA[Colombia Médica]]></journal-title>
<abbrev-journal-title><![CDATA[Colomb. Med.]]></abbrev-journal-title>
<issn>1657-9534</issn>
<publisher>
<publisher-name><![CDATA[Universidad del Valle]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1657-95342007000200008</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[La resistencia de bacterias a antibióticos, antisépticos y desinfectantes una manifestación de los mecanismos de supervivencia y adaptación]]></article-title>
<article-title xml:lang="en"><![CDATA[Resistance to bacterial antibiotics, antiseptics and disinfectants a manifestation of the survival and adaptation mechanisms]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cabrera]]></surname>
<given-names><![CDATA[Cristina Eugenia]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gómez]]></surname>
<given-names><![CDATA[Rommel Fabián]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Zúñiga]]></surname>
<given-names><![CDATA[Andrés Edmundo]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,Universidad Libre Seccional Cali Facultad de Ciencias de la Salud ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2007</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2007</year>
</pub-date>
<volume>38</volume>
<numero>2</numero>
<fpage>149</fpage>
<lpage>158</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S1657-95342007000200008&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S1657-95342007000200008&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S1657-95342007000200008&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[La resistencia a múltiples sustancias es un problema de salud pública que se viene observando a nivel mundial después de la aparición de los antibióticos. El uso indiscriminado de los antibióticos y la presión selectiva ambiental realizada por antisépticos y desinfectantes ha generado una respuesta de supervivencia en los microorganismos,que los capacita para evadir con eficiencia la acción bactericida de algunos agentes. En la actualidad se intenta dilucidar si hay mecanismos compartidos entre antibióticos, antisépticos y desinfectantes que les permita a las bacterias y otros microorganismos activar genes que potencialmente expresen los cinco mecanismos propuestos hasta ahora como respuesta evolutiva a la intervención humana. La presente revisión examina el estado del arte de los mecanismos mencionados,con énfasis en los que actualmente utilizan las bacterias que causan brotes de resistencia en centros hospitalarios.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Resistance to multiple substances is a problem of public health coming to world-wide level observation since the appearance of antibiotics. Indiscriminate use of antibiotics and the environmental selective pressure made by antiseptics and disinfectants have generated a survival answer in the microorganisms, enabling them to efficiently evade the bactericidal action of some agents. Nowadays the time has come to try to explain if mechanisms shared among antibiotics, antiseptics and disinfectants allow bacteria and other germs to activate genes that potentially express the five mechanisms proposed until now as an evolutionary answer to man’s intervention. The present review examines the state-of-the-art of the mentioned mechanisms,with emphasis about the resistance mechanisms performed by nosocomial bacteria in hospitals centers.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Resistencia bacteriana a drogas]]></kwd>
<kwd lng="es"><![CDATA[Antisépticos]]></kwd>
<kwd lng="es"><![CDATA[Antibióticos]]></kwd>
<kwd lng="es"><![CDATA[Desinfectantes]]></kwd>
<kwd lng="en"><![CDATA[Bacterial drugs resistance]]></kwd>
<kwd lng="en"><![CDATA[Antiseptics]]></kwd>
<kwd lng="en"><![CDATA[Antibiotics]]></kwd>
<kwd lng="en"><![CDATA[Disinfectants]]></kwd>
</kwd-group>
</article-meta>
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