<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1657-9534</journal-id>
<journal-title><![CDATA[Colombia Médica]]></journal-title>
<abbrev-journal-title><![CDATA[Colomb. Med.]]></abbrev-journal-title>
<issn>1657-9534</issn>
<publisher>
<publisher-name><![CDATA[Universidad del Valle]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1657-95342021000404287</article-id>
<article-id pub-id-type="doi">10.25100/cm.v52i4.4287</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Community-acquired pneumonia: comparison of three mortality prediction scores in the emergency department]]></article-title>
<article-title xml:lang="es"><![CDATA[Neumonía adquirida en la comunidad: comparación de tres puntuaciones de predicción de mortalidad en el servicio de urgencias]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hincapié]]></surname>
<given-names><![CDATA[Carolina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ascuntar]]></surname>
<given-names><![CDATA[Johana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[León]]></surname>
<given-names><![CDATA[Alba]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Jaimes]]></surname>
<given-names><![CDATA[Fabián]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Antioquia Grupo Académico de Epidemiología Clínica ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Antioquia School of Medicine Department of Internal Medicine]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<volume>52</volume>
<numero>4</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S1657-95342021000404287&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S1657-95342021000404287&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S1657-95342021000404287&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Background:  qSOFA is a score to identify patients with suspected infection and risk of complications. Its criteria are like those evaluated in prognostic scores for pneumonia (CRB-65 - CURB-65), but it is not clear which is best for predicting mortality and admission to the ICU.  Objective:  Compare three scores (CURB-65, CRB-65 and qSOFA) to determine the best tool to identify emergency department patients with pneumonia at increased risk of mortality or intensive care unit (ICU) admission.  Methods:  Secondary analysis of three prospective cohorts of patients hospitalized with diagnosis of pneumonia in five Colombian hospitals. Validation and comparison of the score´s accuracies were performed by means of discrimination and calibration measures.  Results:  Cohorts 1, 2 and 3 included 158, 745 and 207 patients, with mortality rates of 32.3%, 17.2% and 18.4%, and admission to ICU was required for 52.5%, 43.5% and 25.6%, respectively. The best AUC-ROC for mortality was for CURB-65 in cohort 3 (AUC-ROC=0.67). The calibration was adequate (p&gt;0.05) for the three scores.  Conclusions:  None of these scores proved to be an appropriate predictor for mortality and admission to the ICU. Furthermore, the CRB 65 exhibited the lowest discriminative ability.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: el qSOFA es un nuevo puntaje propuesto para ayudar a identificar pacientes con sospecha de infección y con alta probabilidad de desarrollar complicaciones graves. Los criterios del qSOFA son similares a los evaluados en los puntajes de pronóstico usados tradicionalmente en neumonía (CRB-65 y CURB-65), pero no está claro cuál es mejor para predecir la mortalidad y la admisión a la UCI en pacientes con neumonía en el servicio de urgencias  Objetivo: comparar tres puntajes (CURB-65, CRB-65 y qSOFA) para determinar la mejor herramienta para identificar en servicios de urgencias a los pacientes con neumonía con mayor riesgo de mortalidad o ingreso en la unidad de cuidados intensivos (UCI).  Métodos:  análisis secundario de datos de tres estudios de cohorte prospectivos con pacientes atendidos por urgencias con diagnóstico de neumonía en 5 hospitales de Colombia. Se realizó validación y comparación de la exactitud de los puntajes por medio de medidas de discriminación y de calibración.  Resultados: las cohortes 1, 2 y 3 incluyeron 158, 745 y 207 pacientes, con mortalidad de 32.3%, 17.2% y 18.4%, respectivamente. Se requirió la admisión a la UCI para 52.5%, 43.5% y 25.6% pacientes3, respectivamente. La mejor AUC-ROC para mortalidad fue para CURB-65 en la cohorte 3 (AUC-ROC= 0.67). La calibración de los modelos fue adecuada para los tres puntajes (P&gt;0.05).  Conclusiones: Ninguno de estos puntajes demostró ser un predictor adecuado de mortalidad e ingreso en UCI. Además, el CRB 65 mostró la capacidad discriminativa más baja.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Sepsis]]></kwd>
<kwd lng="en"><![CDATA[pneumonia]]></kwd>
<kwd lng="en"><![CDATA[clinical decision rules]]></kwd>
<kwd lng="en"><![CDATA[mortality]]></kwd>
<kwd lng="es"><![CDATA[Sepsis]]></kwd>
<kwd lng="es"><![CDATA[neumonía]]></kwd>
<kwd lng="es"><![CDATA[reglas de decisión clínica]]></kwd>
<kwd lng="es"><![CDATA[mortalidad]]></kwd>
</kwd-group>
</article-meta>
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