<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1794-2470</journal-id>
<journal-title><![CDATA[Nova]]></journal-title>
<abbrev-journal-title><![CDATA[Nova]]></abbrev-journal-title>
<issn>1794-2470</issn>
<publisher>
<publisher-name><![CDATA[Universidad Colegio Mayor de Cundinamarca]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1794-24702017000100011</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Caracterización morfológica y Evaluación clínica de sustitutos óseos de origen porcino de la casa 3Biomat para su aplicación en lesiones óseas bimaxilares]]></article-title>
<article-title xml:lang="en"><![CDATA[Morphological characterization and clinical evaluation of porcine bone substitutes of the 3Biomat house for its application in bimaxillary bone lesions]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gallón Nausa]]></surname>
<given-names><![CDATA[Julian]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Castro Haiek]]></surname>
<given-names><![CDATA[Diego Ernesto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Pontificia Universidad Javeriana  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Pontificia Universidad Javeriana  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2017</year>
</pub-date>
<volume>15</volume>
<numero>27</numero>
<fpage>11</fpage>
<lpage>23</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S1794-24702017000100011&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S1794-24702017000100011&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S1794-24702017000100011&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Objetivo. Realizar la caracterización morfológica y la evaluación clínica de sustitutos óseos de origen porcino, como material para la regeneración y reconstrucción de tejido óseo afectado en lesiones óseas bimaxilares.  Método. Se analizaron características morfológicas de los materiales para regeneración (dispositivos médicos implantables) Biomec Cx y Biomod, el primero es una membrana acelular de submucosa intestinal y el segundo es sustituto óseo particulado y desmineralizado, ambos de origen porcino, por medio de técnicas de coloración y microscopía, con el objetivo de ver celularidad, organización de las fibras colágenas y tamaños de las partículas. Adicionalmente, se realizó un estudio de tipo comparativo prospectivo, con una muestra intencional de 31 pacientes, en los que se hicieron un total de 83 implantes. Los procedimientos quirúrgicos efectuados fueron: implante pos exodoncia más injerto óseo, implante dental e injerto óseo en el mismo tiempo quirúrgico e injerto óseo con un tiempo de 4 meses de integración para la colocación de implantes dentales. Para la evaluación del efecto regenerativo en los diferentes procedimientos quirúrgicos se interpretaron controles clínicos y radiográficos en los que se miró el comportamiento de la cresta ósea marginal. También se realizaron análisis histológicos de biopsias de tejido óseo regenerado.  Resultados. En la caracterización morfológica se encontró que los materiales para regeneración son acelulares. La matriz formada por las fibras de colágeno del sustituto Biomec CX presenta una organización y espacios intersticiales que permiten una buena migración celular. El producto Biomod mostró una densidad y tamaño de partícula adecuada para el proceso regenerativo. En la evaluación clínica, todas las diferencias (mesial y distal) de los meses evaluados en relación con la ganancia de hueso, son estadísticamente significativas; prueba t pareada, p &lt; 0,01 y ANOVA. El aumento promedio en 4 meses fue 0,235mm por mesial (57,3%) y 0,237mm por distal (56,7%).  Conclusiones. A partir de los resultados obtenidos tanto en las características morfológicas como en la evaluación clínica de los sustitutos Biomec CX y Biomod, se comprobó que son materiales aptos para su uso en procesos regenerativos en los que se presenten lesiones óseas bimaxilares.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Objective. To perform the morphological characterization and clinical evaluation of porcine bone substitutes as a material for the regeneration and reconstruction of affected bone tissue in bimaxillary bone lesions.  Method. Morphological characteristics of Biomec Cx and Biomod (implantable medical devices) regeneration materials were analyzed, the first is an acellular membrane of the intestinal submucosa and the second is a particle and demineralized bone substitute, both of porcine origin, by techniques of coloration and microscope with the objective of search the cellularity, organization of collagen fibers and particle sizes. Then a prospective comparative study was conducted with an intentional sample of 31 patients in which a total of 83 implants were made. The surgical procedures were: Post-extraction implant plus bone graft, dental implant- bone graft at the same time and bone graft with a time of 4 months of integration for the placement of dental implants. For the evaluation of the regenerative effect in the different surgical procedure we interpreted clinical and radiographic controls with the behavior of the marginal bone crest. Histological analyzes of biopsies of regenerated bone were also performed.  Results. In the morphological characterization it was found that the materials for regeneration are acellular. The matrix formed by the collagen fibers of the substitute Biomec CX presents an organization and interstitial spaces that allow a good cellular migration. The Biomod product showed a density and particle size suitable for the regenerative process. In the clinical evaluation, all the differences (mesial and distal) of the months evaluated in relation to the bone gain, are statistically significant; T-test, p &lt;0.01 and ANOVA. The average increase in 4 months was 0.235mm per mesial (57.3%) and 0.237mm per distal (56.7%).  Conclusions. Based on the results obtained both in the morphological characteristics and in the clinical evaluation of the substitutes Biomec CX and Biomod, it was verified that they are suitable materials for use in regenerative processes in which bimaxillary bone lesions are present.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Regeneración ósea]]></kwd>
<kwd lng="es"><![CDATA[Sustituto óseo]]></kwd>
<kwd lng="es"><![CDATA[Osteoconductivo]]></kwd>
<kwd lng="es"><![CDATA[Osteoinductivo]]></kwd>
<kwd lng="es"><![CDATA[Lesión ósea]]></kwd>
<kwd lng="en"><![CDATA[Bone regeneration]]></kwd>
<kwd lng="en"><![CDATA[Bone substitution]]></kwd>
<kwd lng="en"><![CDATA[Osteoconductive]]></kwd>
<kwd lng="en"><![CDATA[Osteoinductive]]></kwd>
<kwd lng="en"><![CDATA[Bone injury]]></kwd>
</kwd-group>
</article-meta>
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