Abstract

DIAZ RODRIGUEZ, María Cecilia; ALONSO NINO, Mónica Alexandra  and  CAMARGO CAMARGO, Loida. Optic neuromyelitis in relation with juvenile idiopathic arthritis: A case report. Rev.Colomb.Reumatol. [online]. 2022, vol.29, n.4, pp.390-394.  Epub Aug 18, 2023. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2021.01.007.

Optic neuromyelitis (ONM), also called neuromyelitis optica spectrum (Neuromyelitis Optica Spectrum Disorders, NMOSD) is recognized as an inflammatory autoimmune demyelinating disease of the central nervous system, mediated by autoantibodies against the aquaporin-4 receptor (AQP4-IgG). It predominantly affects the optic nerves and the spinal cord.1-3 It is known that patients with immune disorders are more likely to present other autoimmune diseases, but the relation between juvenile idiopathic arthritis and ONM has not been completely described.5 In this paper, we report a case of a patient with juvenile idiopathic arthritis, presenting with a rapidly progressive neurological condition, who is treated with biological drugs.1-4

Keywords : Aquaporin 4; Juvenile idiopathic arthritis; NMOSD; AQP4-IgG.

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