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Revista Colombiana de Reumatología
Print version ISSN 0121-8123
Abstract
NAVARRO, Erika-Paola et al. Clinical spectrum of IgG4-related disease in Colombia. Rev.Colomb.Reumatol. [online]. 2018, vol.25, n.1, pp.69-74. ISSN 0121-8123. https://doi.org/10.1016/j.rcreu.2016.12.002.
IgG4-related disease is an inflammatory systemic condition noted by the infiltration of different organs by IgG4-bearing plasma cells, as well as elevated serum IgG4 levels. Diagnosis of this condition is complex, and clinical findings are not particularly indicative. In this case series, a description is presented on 4 patients with a wide spectrum of clinical manifestations, in whom, after ruling out different options, a diagnosis of IgG4 related disease was confirmed. Despite this disease not being common, it should be considered among the options whenever multiple organs are affected. This report of patients with IgG4-related disease in Colombia highlights a wide spectrum of clinical presentations, including subglottic stenosis, autoimmune pancreatitis, retroperitoneal fibrosis, and systemic compromise.
Keywords : IgG4 related disease; Ormond's disease; Mikulicz syndrome; Autoimmune pancreatitis.