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Revista Colombiana de Biotecnología

Print version ISSN 0123-3475

Abstract

TORRES SAN MIGUEL, Christopher René; URRIOLAGOITIA CALDERON, Guillermo; URRIOLAGOITIA SOSA, Guillermo  and  HERNANDEZ GOMEZ, Luis Héctor. Numerical analysis of intrabronchial prosthesis used for the treatment of lung cancer. Rev. colomb. biotecnol [online]. 2010, vol.12, n.2, pp.41-54. ISSN 0123-3475.

In Mexico, the mortality rate due to bronchial respiratory sickness is placed in the sixth position, according to statistics from the National Institute of Breathing Sickness (INER), so it is convenient to increment the efficiency of treatments for those pathologies. The intrabronchial valve is a recommended alternative method; being it main objective to avoid invasive surgery and increase the time and quality of patient´s life. Within this work a biomechanical analysis of an IBV® valve is carried out. Regarding the numerical analysis, the dimensions and mechanical properties of the valve were proposed based on catalogues published by the manufacturer as more reliable information was not available in the open literature. As a result, a new model was developed in which both materials Nitinol® and Silastic® are considered as the main valve materials. The proposed working conditions assume that the valve is implanted in folded form at the bronchus and then anchored when it is unfolded. Finite Element Method (FEM) was used to simulate the proposed working conditions. Results obtained show the structural performance and the level of stress generated in the implant during the breathing cycle. In addition, it provides the knowledge to generate a new device that could emulate the performance of these implants and develop a more efficient treatment this disease.

Keywords : Shape memory alloys; lung cancer; intrabronchial valves.

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