Introduction:

Fungal infective endocarditis is an aggressive and infrequent disease, considered an emergency in hospital services. Candida mortality is around 50-80% in all cases. The Candida lusitaniae mainly affects immunocompromised patients with chronic venous access and the use of broad-spectrum antibiotics.

Case report:

A minor infant is presented who is diagnosed with fungemia and infective endocarditis due to Candida lusitaniae in a native valve secondary to surgery by transposition of large vessels.

Discussion and Conclusions:

Candida lusitaniae infectious endocarditis is very rare, with a prevalence of less than 2% constituting a challenging scenario in clinical practice. The characteristics of fungemia and endocarditis already defined in the world literature are described. Early detection and a vertiginous therapeutic intervention are essential, since; latent infection, antifungal resistance and delay in diagnosis lead to a threatening condition for the patient’s life.

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